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Funding: Kitware to Develop Quantitative Cancer Assessment Environment

posted Oct 15, 2012, 8:44 AM by Stephen Aylward
Kitware today announces the award of $298,436 in Phase I SBIR funding from the National Institutes of Health.  In this Phase I project, Kitware and researchers from the University of North Carolina at Chapel Hill will develop a quantitative, non-invasive diagnostic approach to assessing tumor growth and treatment outcomes using ultrasound. The team will first leverage a new dual-frequency ultrasound probe and a microbubble contrast agent that work together to enable the rapid acquisition of high-contrast and high-resolution 3D images of microscopic blood vessels in and around tumors. Second, building upon Kitware’s TubeTK software library, the team will investigate algorithms for assessing tumor malignancy and response to therapy by evaluating morphological characteristics of those microvessels. Kitware’s prior work involving MRI suggests that microvascular metrics are reliable predictors of tumor malignancy and response to therapy. This research may ultimately provide clinicians with an inexpensive, safe, and highly-effective diagnostic tool for the quantitative assessment of cancer.